Thermo Fisher Scientific REA Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Rabbit Polyclonal Antibody. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제. 4°C 또는 -20°C에서 안정적 보관 가능. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human REA. Recombinant protein control fragment (Product #RP-97906). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856526 |
Product Specific Information
Immunogen sequence:
AQRAQFLVEK AKQEQRQKIV QAEGEAEAAK MLGEALSKNP GYIKLRKIRA AQNISKTIAT SQNRIYLTAD NLVLNLQDES FTRGSDSLIK GKK
Target Information
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.
This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.
It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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