Thermo Fisher Scientific CT74 Polyclonal Antibody
Thermo Fisher Scientific CT74 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 폴리클로날 항체입니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용됩니다. KLH 접합 합성 펩타이드 면역원으로 제작되었으며, 고순도 Protein A 정제 및 안정적 저장 조건을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CCDC36/CT74, amino acids 131–230 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Acts likely by forming a complex with MEI4 and REC114, which activates DSB formation in unsynapsed regions — an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC), or meiotic surveillance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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