Thermo Fisher Scientific ZC3H12D Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZC3H12D. Recombinant protein control fragment (Product #RP-94958). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZC3H12D,uniProtId:A2A288-1,ncbiNodeId:9606,antigenRange:14-86,antigenLength:527,antigenImageFileName:PA5-57865_ZC3H12D_A2A288-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57865_ZC3H12D_A2A288-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649799

Product Specific Information

Immunogen sequence: GYDREDVLRV LGKLGEGALV NDVLQELIRT GSRPGALEHP AAPRLVPRGS CGVPDSAQRG PGTALEEDFR TLA

Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 64%.

Target Information

ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.