Thermo Fisher Scientific ZC3H12D Polyclonal Antibody
Thermo Fisher Scientific의 ZC3H12D Polyclonal Antibody는 인간 ZC3H12D 단백질을 인식하는 토끼 다클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZC3H12D. Recombinant protein control fragment (Product # RP-94958) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649799 |
Product Specific Information
Immunogen sequence:
GYDREDVLRV LGKLGEGALV NDVLQELIRT GSRPGALEHP AAPRLVPRGS CGVPDSAQRG PGTALEEDFR TLA
Highest antigen sequence identity to the following orthologs:
- Mouse: 63%
- Rat: 64%
Target Information
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein thought to be involved in macrophage activation, host immunity, and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages increases after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it may play a different role in host immunity and inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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