Thermo Fisher Scientific NKX6.1 (Marker for Pancreatic and Duodenal Neuroendocrine Tumors) Monoclonal Antibody (NKX61/2561)
췌장 및 십이지장 신경내분비 종양 마커 NKX6.1 단일클론 항체. 인간 시료에 반응하며 IHC(P), IHC(PFA), Peptide Array에 사용 가능. 단백질 A/G 정제, 1 mg/mL 농도, PBS(pH 7.4) 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NKX61/2561 |
| Immunogen | Recombinant full-length human NKX6.1 protein (amino acids 1–367, UniProt ID: P78426-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NKX6.1 is a bi-functional transcription factor with roles in both the central nervous system and the pancreas. It regulates gene expression to enable the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. NKX6.1 interacts with Pax6 and Pdx-1, likely near the 60 amino acid homeobox DNA-binding domain. Due to its involvement in beta-cell function and CNS development, NKX6.1 is an important target for diabetes and neurological disease research.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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