Thermo Fisher Scientific Mast Cell Chymase Polyclonal Antibody
Mast Cell Chymase를 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. E.coli 유래 CMA1 단백질을 면역원으로 사용하였으며, 항원 친화 크로마토그래피로 정제되었습니다. 500 µg/mL 농도로 동결건조 상태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human CMA1 recombinant protein (Position: I22–N247) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746169 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
This gene product is a chymotryptic serine proteinase belonging to the peptidase family S1. It is expressed in mast cells and functions in extracellular matrix degradation, regulation of submucosal gland secretion, and generation of vasoactive peptides. In cardiovascular tissues, this protein primarily converts angiotensin I to angiotensin II, influencing blood pressure regulation and contributing to conditions such as hypertension, cardiac hypertrophy, and heart failure. The gene is located on chromosome 14q11.2 within a cluster of protease-encoding genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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