Thermo Fisher Scientific Opsin 3 Polyclonal Antibody
Opsin 3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화성 크로마토그래피 정제. 1 mg/mL 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific Opsin 3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OPN3 (Accession Q9H1Y3), corresponding to amino acid residues A169–A219 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854496 |
Product Specific Information
Antibody detects endogenous levels of total OPN3.
Target Information
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins expressed in extraocular tissues.
Opsin 3 is strongly expressed in brain and testis, and weakly in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. It may also be expressed in the retina. The protein exhibits canonical photoreceptive opsin features and may play a role in encephalic photoreception.
Strong expression is observed in the brain, particularly in the preoptic area and paraventricular nucleus of the hypothalamus. It shows patterned expression in cerebral cortex, cerebellar Purkinje cells, subsets of striatal neurons, thalamic nuclei, and interneurons in the ventral horn of the spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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