Thermo Fisher Scientific NR5A1 Monoclonal Antibody (OTI1B4), TrueMAB
Human NR5A1 단백질(아미노산 1-262)에 특이적인 마우스 단클론 항체. Western blot과 IHC(P)에서 검증됨. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 스테로이드 생성 관련 연구 및 내분비계 발달 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–262 of human NR5A1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2) common to nuclear steroid receptors, which are necessary for interaction with other nuclear receptors and coactivators/corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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