Thermo Fisher Scientific MVP Monoclonal Antibody (1032), Biotin
Human 및 Rat 시료에서 Major Vault Protein 검출용 Biotin 결합 단클론 항체. Western blot, IHC, Flow cytometry, IP 등 다양한 응용 가능. Protein G 정제, 4°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific MVP Monoclonal Antibody (1032), Biotin
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
| Flow Cytometry (Flow) | Assay-dependent | – |
| Immunoprecipitation (IP) | 2 µg/mL | – |
| Gel Shift (GS) | 1 mg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1032 |
| Immunogen | Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983486 |
Product Specific Information
MA5-13868 targets Major Vault Protein (MVP) in FACS, GS, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.
The immunogen is proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.
Target Information
This gene encodes the major vault protein, a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport.
This protein mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells.
Overexpression of this protein is a potentially useful marker of clinical drug resistance.
This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are identical in both transcripts.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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