Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI8A1), TrueMAB
AK1 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 완충액에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2500–1:5000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Full length human recombinant protein of human AK1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
AK1 is found in the cytosol of skeletal muscle, brain, and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart.
AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia, where a mutation in the AK1 gene reduces the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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