Thermo Fisher Scientific SFTPC Polyclonal Antibody
Human SFTPC 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 폐 관련 단백질 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SFTPC. Recombinant protein control fragment (Product #RP-90440) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647199 |
Product Specific Information
Immunogen sequence:
PEAQQRLALS EHLVTTATFS IGSTGLVVYD YQQLLIAYKP APGTCCYIMK IAPESIPSLE ALTRKVHNFQ AKPAVPTSKL GQAEGRDAGS APSGGDPAFL GMAVSTLCG
Antigen sequence identity:
- Mouse: 75%
- Rat: 76%
Target Information
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins, including SPA, SPB, SPC, and SPD. The surfactant is secreted by alveolar cells and maintains lung tissue stability by reducing the surface tension of fluids coating the lung.
Multiple mutations in this gene are associated with pulmonary surfactant metabolism dysfunction type 2 (pulmonary alveolar proteinosis due to surfactant protein C deficiency) and interstitial lung disease in infants, children, and adults.
Alternatively spliced transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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