Thermo Fisher Scientific SSX4 Monoclonal Antibody (3E10)
SSX4 단백질을 인식하는 Mouse monoclonal antibody(3E10)로 Western blot 및 ELISA에 적합. Human 시료 반응성. 액상 형태로 -20°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E10 |
| Immunogen | SSX4 (NP_005627, 91 a.a. approximately 188 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RNQVERPQMT FGSLQRIFPK IMPKKPAEEE NGLKEVPEAS GPQNDGKQLC PPGNPSTLEK INKTSGPKRG KHAWTHRLRE RKQLVVYEEI SDPEEDDE
Target Information
SSX4 belongs to the SSX family and contains one KRAB-related domain. SSX4 may act as a modulator of transcription.
The SSX family proteins are highly homologous synovial sarcoma X (SSX) breakpoint proteins that may function as transcriptional repressors.
They can elicit humoral and cellular immune responses in cancer patients and are potential targets for cancer vaccine-based immunotherapy.
SSX1, SSX2, and SSX4 genes are involved in the t(X;18) translocation found in all synovial sarcomas, resulting in fusion of the synovial sarcoma translocation gene on chromosome 18 with one of the SSX genes on chromosome X.
Chromosome Xp11 contains two identical copies of SSX4 and SSX4B in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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