Thermo Fisher Scientific BBS2 Polyclonal Antibody
Thermo Fisher Scientific의 BBS2 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot 및 IHC(P) 실험에 적합하며, 고순도 친화 크로마토그래피 정제. BBS2 단백질의 내인성 수준 검출에 사용.
- 카탈로그번호
- PA5100008
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BBS2 (Accession Q9BXC9), corresponding to amino acid residues T639–K689 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815538 |
Product Specific Information
Antibody detects endogenous levels of total BBS2.
Target Information
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation, and mental retardation.
The proteins encoded by BBS gene family members are structurally diverse, and the similar phenotypes exhibited by mutations in BBS genes are likely due to their shared roles in cilia formation and function.
Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport.
The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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