Thermo Fisher Scientific SF3B5 Polyclonal Antibody
Human SF3B5 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤 포함. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SF3B5. Recombinant protein control fragment (Product #RP-94946). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647181 |
Product Specific Information
- Immunogen sequence:
DRYTIHSQLE HLQSKYIGTG HADTTKWEWL VNQHRDSYCS YMGHFDLLNY FAIAENESKA RVRFNLMEKM LQPCGPPADK PEEN - Highest antigen sequence identity to orthologs:
Mouse – 99%, Rat – 99%
Target Information
SF3B5 is a protein coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. The SF3B complex is required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of the SF3A/SF3B complex upstream of the branch site is essential and may anchor U2 snRNP to the pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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