Thermo Fisher Scientific SRSF11 Polyclonal Antibody
Rabbit polyclonal antibody against human SRSF11, validated for IHC(P) and ICC/IF. Recognizes recombinant SRSF11 protein. Suitable for research use in RNA splicing studies. Supplied as a liquid, 0.2 mg/mL in PBS with 40% glycerol.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SRSF11. Recombinant protein control fragment (Product # RP-88824) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647939 |
Product Specific Information
Immunogen sequence:
LLPTPNPLTQ IGAVPLAALG APTLDPALAA LGLPGANLNS QSLAADQLLK LMSTVDPKLN HVAAGLVSPS LKSDTSSKEI EEAMKRVREA QSLISAAIEP DKKEEKRRHS RSRSR
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
Pre-mRNA splicing enhancer elements are short RNA sequences that activate weak splice sites in nearby introns, essential for accurate splice site recognition and control of alternative splicing. These enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, including SC35, 9G8, SRp20, and SF2/ASF.
The SR factor family contains one or more RNA recognition motifs (RRM) and an SR-rich domain, playing key roles in constitutive and alternative splicing.
SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the SR splicing factor family. SFRS11 may function in pre-mRNA splicing and contains one RRM domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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