Thermo Fisher Scientific VIM Monoclonal Antibody (OTI3G4), TrueMAB

Applications

Tested Application

• Western Blot (WB)

Tested Dilution

• 1:200–1:1,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Vimentin is a developmentally regulated intermediate filament protein found in cells of mesenchymal origin. It plays a role in intracellular protein transport between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific intermediate filament proteins.
It is also involved in steroid synthesis regulation by serving as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase triggers filament breakdown and cytoskeletal changes, facilitating cholesterol transport to mitochondria and enhancing steroid synthesis.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

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