Thermo Fisher Scientific PHF7 Polyclonal Antibody
인간 PHF7 단백질을 인식하는 Rabbit Polyclonal 항체로, 면역세포화학(ICC/IF)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다. 단백질 발현 및 정자형성 연구에 유용합니다.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PHF7. Recombinant protein control fragment (Product # RP-104292) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645500 |
Product Specific Information
Immunogen sequence:
IHIPDRDAAW ELEPGAFSDL YQRYQHCDAP ICLYEQGRDS FEDEGRWCLI LCATCGSHGT HRDCSSLRSN SKKWECEE
Sequence identity with orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells.
In the testis, this gene is expressed in Sertoli cells but not in germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia.
The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation.
This protein localizes to the nucleus of transfected cells and is implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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