Thermo Fisher Scientific GLUR4 Polyclonal Antibody
GLUR4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human GLUR4, amino acids 501–600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both containing glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors, co-localized with NMDA receptors in many synapses, consist of seven subunits (GluR1–GluR7). They are primarily responsible for fast excitatory neurotransmission by glutamate, while NMDA receptors are characterized by slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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