Thermo Fisher Scientific PDZK1 Monoclonal Antibody (1E9)
Thermo Fisher Scientific PDZK1 Monoclonal Antibody (1E9)은 인간 PDZK1 단백질을 인식하는 mouse IgG2a 항체로, Western blot과 ELISA에 적합합니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 세포 내 단백질 상호작용 및 막 단백질 발현 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E9 |
| Immunogen | PDZK1 (AAH06496, 1–519 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MTSTFNPREC KLSKQEGQNY GFFLRIEKDT EGHLVRVVEK CSPAEKAGLQ DGDRVLRING VFVDKEEHMQ VVDLVRKSGN SVTLLVLDGD SYEKAVKTRV DLKELGQSQK EQGLSDNILS PVMNGGVQTW TQPRLCYLVK EGGSYGFSLK TVQGKKGVYM TDITPQGVAM RAGVLADDHL IEVNGENVED ASHEEVVEKV KKSGSRVMFL LVDKETDKRH VEQKIQFKRE TASLKLLPHQ PRIVEMKKGS NGYGFYLRAG SEQKGQIIKD IDSGSPAEEA GLKNNDLVVA VNGESVETLD HDSVVEMIRK GGDQTSLLVV DKETDNMYRL AHFSPFLYYQ SQELPNGSVK EAPAPTPTSL EVSSPPDTTE EVDHKPKLCR LAKGENGYGF HLNAIRGLPG SFIKEVQKGG PADLAGLEDE DVIIEVNGVN VLDEPYEKVV DRIQSSGKNV TLLVCGKKAY DYFQAKKIPI VSSLADPLDT PPDSKEGIVV ESNHDSHMAK ERAHSTASHS SSNSEDTEM
Target Information
PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cell apical domains. It may coordinate various regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster functionally dependent proteins and modulate trafficking and activity of associated membrane proteins. It may also play roles in multidrug resistance mechanisms through interactions with ABCC2 and PDZK1IP1, and potentiate CFTR chloride channel activity. PDZK1 connects SCARB1 with intracellular cholesterol transport machinery and may regulate proximal tubular Na(+)-dependent inorganic phosphate cotransport, contributing to tubule function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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