Thermo Fisher Scientific APEH Polyclonal Antibody
Rabbit polyclonal antibody against human APEH protein. Recognizes recombinant APEH antigen (191–281 aa). Supplied as a liquid, unconjugated form. Suitable for research use only; store at 4°C short term or -20°C long term.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human APEH (amino acids 191–281) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856395 |
Product Specific Information
Immunogen sequence:
IARLKKPDQA IKGDQFVFYE DWGENMVSKS IPVLCVLDVE SGNISVLEGV PENVSPGQAF WAPGDAGVVF VGWWHEPFRL GIRFCTNRRS A
Target Information
APEH (acylpeptide hydrolase) catalyzes the hydrolysis of terminal acetylated amino acids from small acetylated peptides. The resulting acetyl amino acid is further processed into acetate and a free amino acid by aminoacylase.
The APEH gene is located on chromosome 3 (3p21), in proximity to the aminoacylase gene. Deletions in this region are associated with reduced aminoacylase activity.
APEH is a homotetrameric enzyme (~300 kDa), with each subunit containing 732 amino acids, and plays a vital role in degrading oxidatively damaged proteins in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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