Thermo Fisher Scientific Complement C5a Monoclonal Antibody (D4)
인체, 돼지, 쥐 시료에서 Complement C5a 단백질을 검출하기 위한 모노클로날 항체. Western blot과 IHC(파라핀) 실험에 적합. Recombinant Human C5a 단백질을 면역원으로 사용. 고순도의 Protein A/G 정제, 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–5 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–30 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D4 |
| Immunogen | Recombinant Human C5a protein, Thr678–Arg751 (Accession #P01031) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094026 |
Target Information
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. It is composed of alpha and beta polypeptide chains linked by a disulfide bridge. The activation peptide C5a, an anaphylatoxin with potent spasmogenic and chemotactic activity, is derived from the alpha chain via cleavage with a convertase. The C5b cleavage product forms a complex with complement component C6, serving as the basis for the membrane attack complex formation. Mutations in this gene cause complement component 5 deficiency, leading to recurrent infections. Defects are also associated with susceptibility to liver fibrosis and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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