Thermo Fisher Scientific SULT2A1 Polyclonal Antibody
Thermo Fisher Scientific의 SULT2A1 Polyclonal Antibody는 인간 SULT2A1 단백질을 인식하는 토끼 다클론 항체로, Western blot과 IHC(P)에서 검증되었습니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로 간 및 부신 조직 내 발현 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SULT2A1. Recombinant protein control fragment (Product # RP-103706) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791760 |
Product Specific Information
Immunogen sequence:
EFVIRDEDVI ILTYPKSGTN WLAEILCLMH SKGDAKWIQS VPIW
Target Information
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids.
SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues.
It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, transcribed from the same gene by alternative splicing. Both isoforms are selective for the sulphation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol.
SULT2B1b is expressed in prostate, skin, placenta, and lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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