
Thermo Fisher Scientific TTK Monoclonal Antibody (OTI13E9), TrueMAB
TTK 단백질을 인식하는 Mouse monoclonal antibody(OTI13E9)로 Western blot에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose)로 안정화. 연구용으로만 사용 가능.
- 카탈로그번호
- CF811813
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 189–464 of human TTK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TTK is a serine/threonine kinase closely related to SPK1, PIM1, and CDC2 serine/threonine kinases.
It is a dual-specificity kinase capable of phosphorylating tyrosine residues as well.
The enzyme consists of a catalytic subunit and a constant regulatory subunit that associates with various regulatory subunits.
The constant regulatory subunit A acts as a scaffold for assembly of the catalytic and variable regulatory B subunits.
TTK encodes an alpha isoform of the constant regulatory subunit A.
Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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