Thermo Fisher Scientific TTK Monoclonal Antibody (OTI13E9), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

TTK is a serine/threonine kinase closely related to SPK1, PIM1, and CDC2 serine/threonine kinases.
It is a dual-specificity kinase capable of phosphorylating tyrosine residues as well.
The enzyme consists of a catalytic subunit and a constant regulatory subunit that associates with various regulatory subunits.
The constant regulatory subunit A acts as a scaffold for assembly of the catalytic and variable regulatory B subunits.
TTK encodes an alpha isoform of the constant regulatory subunit A.
Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.