Thermo Fisher Scientific BCAS4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human BCAS4. Recombinant protein control fragment (Product #RP-95486). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCAS4,uniProtId:Q8TDM0-1,ncbiNodeId:9606,antigenRange:26-117,antigenLength:211,antigenImageFileName:PA5-58549_BCAS4_Q8TDM0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58549_BCAS4_Q8TDM0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638499

Product Specific Information

Immunogen sequence: PVALLMLLVD ADQPEPMRSG ARELALFLTP EPGAEAKEVE ETIEGMLLRL EEFCSLADLI RSDTSQILEE NIPVLKAKLT EMRGIYAKVD RL

Highest antigen sequence identity to the following orthologs: Mouse - 29%, Rat - 29%.

Target Information

The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.