Thermo Fisher Scientific BCAS4 Polyclonal Antibody
Human BCAS4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.7 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCAS4. Recombinant protein control fragment (Product #RP-95486) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638499 |
Product Specific Information
Immunogen sequence:
PVALLMLLVD ADQPEPMRSG ARELALFLTP EPGAEAKEVE ETIEGMLLRL EEFCSLADLI RSDTSQILEE NIPVLKAKLT EMRGIYAKVD RL
Highest antigen sequence identity to the following orthologs:
- Mouse: 29%
- Rat: 29%
Target Information
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region often amplified in breast cancers. It was isolated by cloning a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes.
The BCAS3-BCAS4 fusion transcript is found only in the MCF7 cell line, but BCAS4 is also overexpressed in nine of thirteen breast cancer cell lines.
Although the role of BCAS4 is unknown, its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting roles in multiple tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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