Thermo Fisher Scientific Human MAPK15 (ERK7), His Tag Recombinant Protein

Thermo Fisher Scientific Human MAPK15 (ERK7), His Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
For larger sizes, aliquot preparation may reduce freeze/thaw cycles (aliquots below 20 µL not recommended).
Do not store kinase diluted.
Properly stored at -80°C, guaranteed for 6 months from purchase.

Human MAPK15 (ERK7), N-terminal fragment (M1–R354; NCBI/Protein entry NP_620590.2), N-terminal 4xFLAG-tag and C-terminal HIS8 fusion protein, expressed in Sf9 insect cells.

Features:

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes for convenient use

Related Product:
LanthaScreen™ Eu Kinase Binding Assay

Protein Form: Recombinant
Gene Accession Number: NP_620590.2

Target Information

ERKs are a subfamily of MAPKs implicated in cell growth and differentiation.
Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase regulated by serum and c-Src kinase.
ERK8 down-regulates glucocorticoid receptor transactivation via Hic-5 and negatively regulates androgen receptor and GRα co-activation in a kinase-independent manner, indicating a broader role in nuclear receptor regulation.
Erk8 also acts as a novel effector of RET/PTC3, contributing to RET biological functions.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.