Thermo Fisher Scientific Human MAPK15 (ERK7), His Tag Recombinant Protein
Human MAPK15 (ERK7) recombinant His-tagged protein for kinase assay and binding studies. Expressed in Baculovirus system, purified and supplied in liquid form. Suitable for LanthaScreen™ Kinase Binding Assay. Stable at -80°C for up to 6 months.
- 카테고리
- Protein
- 판매단위
- pk
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Thermo Fisher Scientific Human MAPK15 (ERK7), His Tag Recombinant Protein
Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Baculovirus |
| Amino Acid Sequence | 1–354 |
| Tag | His-tag |
| Molecular Weight | 46.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM HEPES (pH 7.5), 20% glycerol, 100 mM NaCl, 5 mM DTT, 15 mM glutathione |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
For maximum recovery, spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
For larger sizes, aliquot preparation may reduce freeze/thaw cycles (aliquots below 20 µL not recommended).
Do not store kinase diluted.
Properly stored at -80°C, guaranteed for 6 months from purchase.
Human MAPK15 (ERK7), N-terminal fragment (M1–R354; NCBI/Protein entry NP_620590.2), N-terminal 4xFLAG-tag and C-terminal HIS8 fusion protein, expressed in Sf9 insect cells.
Features:
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes for convenient use
Related Product:
LanthaScreen™ Eu Kinase Binding Assay
Protein Form: Recombinant
Gene Accession Number: NP_620590.2
Target Information
ERKs are a subfamily of MAPKs implicated in cell growth and differentiation.
Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase regulated by serum and c-Src kinase.
ERK8 down-regulates glucocorticoid receptor transactivation via Hic-5 and negatively regulates androgen receptor and GRα co-activation in a kinase-independent manner, indicating a broader role in nuclear receptor regulation.
Erk8 also acts as a novel effector of RET/PTC3, contributing to RET biological functions.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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