Thermo Fisher Scientific MOV10L1 Polyclonal Antibody
MOV10L1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 액상 형태로 제공됨. 인간 MOV10L1 내부 영역에서 유래한 합성 펩타이드 면역원 사용. 생식세포 연구 및 piRNA 대사 과정 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MOV10L1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human MOV10L1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555968 |
Target Information
Isoform 1:
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, essential for germline integrity. Acts via the piRNA metabolic process, forming complexes with piRNAs and Piwi proteins to mediate transposon repression through methylation. Involved in the primary piRNA metabolic process, binds to piRNA precursors, and promotes generation of intermediate piRNA fragments loaded onto Piwi proteins. Exhibits 5′–3′ RNA unwinding activity, likely mediating unwinding and funneling of single-stranded piRNA precursor transcripts for processing.
Isoform 2:
May act downstream of MEF2C during heart formation. Functions as a cardiac-specific suppressor of cardiomyocyte hypertrophy and cell cycle progression, potentially through regulation of CDKN1A. Further evidence required.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.