Thermo Fisher Scientific RASA3 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human RASA3. Recombinant protein control fragment (Product #RP-98013). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
RASA3,
uniProtId:
Q14644-1,
ncbiNodeId:
9606,
antigenRange:
736-811,
antigenLength:
834,
antigenImageFileName:
PA5-111244_RASA3_Q14644-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-111244_RASA3_Q14644-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2856654
Product Specific Information
Immunogen sequence: LFNLYMSKLE KMQEACGSKS VYDGPEQEEY STFVIDDPQE TYKTLKQVIA GVGALEQEHA QYKRDKFKKT KYGSQE
Target Information
Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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