Thermo Fisher Scientific CD8b Monoclonal Antibody (H35-17.2)
Mouse CD8b 단백질을 인식하는 Rat IgG2b 단일클론 항체로, ICC/IF, Flow Cytometry, Functional Assay에 적합합니다. 비결합형 액상 형태이며 Protein A/G로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10⁶ cells |
| Functional Assay (Functional) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H35-17.2 |
| Immunogen | Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Human.
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.
The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by antigen presenting cells (APCs) in the context of class I MHC molecules.
The functional coreceptor is either a homodimer (two alpha chains) or a heterodimer (one alpha and one beta chain).
Both chains show significant homology to immunoglobulin variable light chains.
This gene encodes the CD8 beta chain isoforms, with multiple alternatively spliced transcript variants.
A pseudogene located on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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