Thermo Fisher Scientific METRNL Polyclonal Antibody
인간 METRNL 단백질을 인식하는 Rabbit Polyclonal 항체입니다. Western Blot에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. 에너지 대사 및 열 발생 관련 연구에 활용 가능합니다. -20°C 보관, Wet ice 배송.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human METRNL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690429 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 86%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 77%; Rabbit: 86%; Rat: 92%; Yeast: 90%
Target Information
METRNL is a hormone induced following exercise or cold exposure that promotes energy expenditure. It is expressed in skeletal muscle after exercise or in adipose tissue following cold exposure and circulates in the bloodstream. METRNL stimulates energy expenditure associated with browning of white fat depots and improves glucose tolerance. It acts indirectly by activating immune cell subtypes that promote thermogenic and anti-inflammatory gene programs in adipose tissue. It is required for certain cold-induced thermogenic responses, indicating a role in metabolic adaptations to cold temperatures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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