Thermo Fisher Scientific Acetyl-Lysine Polyclonal Antibody
Rabbit polyclonal antibody recognizing acetyl-lysine residues. Suitable for Western blot and other assay-dependent applications. Provided as liquid form, Protein A purified, 1 mg/mL concentration. Stored at -20°C in TBS buffer with glycerol and BSA.
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated acetyl Lysine |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In the nucleus, DNA is tightly packed into nucleosomes, creating a repressive environment for transcription. Acetylation of lysine residues in proteins helps overcome this repression. Both histone and non-histone protein acetylation play roles in transcriptional regulation and chromatin remodeling. Acetylation may induce structural transitions and specific signaling within chromatin domains. Bromodomain recognition of acetylated lysine functions as a regulatory mechanism in protein-protein interactions, influencing various cellular processes such as chromatin remodeling and transcriptional activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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