Thermo Fisher Scientific COG2 Polyclonal Antibody
COG2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 용액 형태로 제공됩니다. 인간 시료 반응성이 있으며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human COG2. Recombinant protein control fragment (Product #RP-94222) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663312 |
Product Specific Information
Immunogen sequence:
VPTTASSYVDS ALKPLFQLQS GHKDKLKQAI IQQWLEGTLS ESTHKYYETV SDVLNSVKKM EESLKRLKQA RKTTPANPVG PSGGMSDDD
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 74%
Target Information
The structure and function of the Golgi apparatus is controlled by multi-protein complexes involved in glycosylation and vesicular transport. The conserved oligomeric Golgi (COG) complex consists of subcomplexes LDLC, SEC34, and GTT, all required for proper Golgi operation.
COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component of the COG complex localized to the cytoplasmic side of the Golgi apparatus. It is essential for Golgi morphology, ribbon formation, and vesicular transport. Abnormal COG2 function may cause cell death, indicating its importance in cell viability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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