
Thermo Fisher Scientific MCFD2 Monoclonal Antibody (5C6)
인간 MCFD2 단백질에 특이적인 마우스 단클론 항체. Western blot에 적합하며 1:1,000 희석으로 검증됨. 단백질 G로 정제된 액상형 항체로 안정적인 TBS/glycerol/BSA buffer에 보관. 연구용으로 ER-Golgi 단백질 수송 연구에 활용 가능.
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Thermo Fisher Scientific MCFD2 Monoclonal Antibody (5C6)
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5C6 |
| Immunogen | Mouse immunized with MCFD2 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause factor V and factor VIII combined deficiency (F5F8D), an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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