Thermo Fisher Scientific MCFD2 Monoclonal Antibody (5C6)

Thermo Fisher Scientific MCFD2 Monoclonal Antibody (5C6)

Applications

• Western Blot (WB)

Tested Dilution: 1:1,000
Publications: -

Product Specifications

Target Information

Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause factor V and factor VIII combined deficiency (F5F8D), an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.