Thermo Fisher Scientific Phospho-Kir6.2 (Thr224) Polyclonal Antibody
Kir6.2 단백질의 Thr224 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human Kir6.2 around the phosphorylation site of Thr224 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the voltage range of channel opening shifts to more positive voltages. Inward rectification mainly results from blockage of outward current by internal magnesium. These channels can be blocked by extracellular barium. Kir6.2 is a subunit of ATP-sensitive potassium channels (KATP) and can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore, while ABCC9 is required for activation and regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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