Thermo Fisher Scientific ENY2 Polyclonal Antibody
ENY2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 시료에 반응. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 안정적 PBS/glycerol 저장.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ENY2 (Accession Q9NPA8), corresponding to amino acid residues H49–A99 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899818 |
Product Specific Information
Antibody detects endogenous levels of total ENY2.
Target Information
ENY2 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ENY2 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. It is also required for nuclear receptor-mediated transactivation and may participate in mRNA export and chromatin positioning by tethering genes to the nuclear periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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