Thermo Fisher Scientific TESPA1 Polyclonal Antibody
Rabbit polyclonal antibody against human TESPA1. Validated for IHC (Paraffin) with dilution 1:1,000–1:2,500. Supplied as liquid, unconjugated, 0.3 mg/mL in PBS with 40% glycerol. For research use only.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TESPA1. Recombinant protein control fragment (Product #RP-106893) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2661934 |
Product Specific Information
Immunogen sequence:
TNTETHPAKDE TFWKRKSRAR KSLFQKNLMG RKVKSLDLSI TQQKWKQSVD RPELRRSLSQ QPQDTFDLEE VQSNSEEEQS QSRWPSRPRH PHHHQT
Highest antigen sequence identity to the following orthologs:
- Mouse: 25%
- Rat: 26%
Target Information
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression is tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency results in failure of positive selection and substantially fewer CD4+ and CD8+ SP cells in the thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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