Thermo Fisher Scientific FAM120B Polyclonal Antibody
FAM120B 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응하며 Protein A로 정제됨. 고농도(1 mg/mL) 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FAM120B (amino acids 65–170) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The transcription factor peroxisome proliferator-activated receptor gamma (PPARγ) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association with various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and during embryonic development. Overexpression of this protein in OP9 pre-adipocytes promotes differentiation into adipocytes, whereas knockdown of PGCC1 expression blocks this process. PGCC1 is homologous to C9orf10 (FAM120A) and is mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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