Thermo Fisher Scientific IGKV2-29 Polyclonal Antibody
IGKV2-29 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot과 Flow Cytometry에 사용 가능. 비결합형 액상 형태로 제공되며, 단기 4℃, 장기 -20℃ 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 80–107 amino acids from the C-terminal region of human IGKV A18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717421 |
Target Information
The V region of the variable domain of immunoglobulin light chains participates in antigen recognition (PubMed:24600447).
Immunoglobulins (antibodies) are membrane-bound or secreted glycoproteins produced by B lymphocytes.
In the recognition phase of humoral immunity, membrane-bound immunoglobulins act as receptors that, upon binding specific antigens, trigger clonal expansion and differentiation into plasma cells secreting immunoglobulins.
Secreted immunoglobulins mediate the effector phase of humoral immunity, leading to antigen elimination (PubMed:20176268, PubMed:22158414).
Each immunoglobulin has two antigen-binding sites formed by the variable domains of heavy and light chains.
These domains are assembled through V-(D)-J rearrangement and can undergo somatic hypermutation to enhance affinity after antigen exposure and selection (PubMed:20176268, PubMed:17576170).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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