Thermo Fisher Scientific UBE3C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

-

ELISA (ELISA)

1 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 970-1083 of human UBE3C (NP_0554862) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBE3C,uniProtId:Q15386-1,ncbiNodeId:9606,antigenRange:970-1083,antigenLength:1083,antigenImageFileName:PA5-110540_UBE3C_Q15386-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110540_UBE3C_Q15386-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.81 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855951

Product Specific Information

Immunogen sequence: PISLEDLKSF TNYSGGYSAD HPVIKVFWRV VEGFTDEEKR KLLKFVTSCS RPPLLGFKEL YPAFCIHNGG SDLERLPTAS TCMNLLKLPE FYDETLLRSK LLYAIECAAG FELS

Target Information

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either Lys-29- or Lys-48-linked polyubiquitin chains. Has preference for Lys-48 linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.