Thermo Fisher Scientific SIAH1 Monoclonal Antibody (2F26)
SIAH1 단백질을 인식하는 Mouse IgM 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 시료에 반응하며, GST 태그가 포함된 재조합 단백질을 면역원으로 사용했습니다. PBS 용액 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F26 |
| Immunogen | SIAH1 (NP_003022, 1 a.a. – approximately 110 a.a.) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSRQTATALP TGTSKCPPSQ RVPALTGTTA SNNDLASLFE CPVCFDYVLP PILQCQSGHL VCSNCRPKLT CCPTCRGPLG SIRNLAMEKV ANSVLFPCKY ASSGCEITLP
Target Information
This gene encodes a protein that is a member of the seven in absentia homolog family.
The protein functions as an E3 ligase involved in ubiquitination and proteasome-mediated degradation of specific proteins.
Its activity has been implicated in:
- Certain forms of Parkinson’s disease
- Regulation of cellular response to hypoxia
- Induction of apoptosis
Alternative splicing results in several transcript variants, some encoding different isoforms and others not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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