Thermo Fisher Scientific CD147/EMMPRIN/Neurothelin Recombinant Rabbit Monoclonal Antibody (BSG/6468R)
CD147/EMMPRIN/Neurothelin 표적의 재조합 단일클론 항체로, 인간 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합합니다. HEK293 세포에서 발현된 Rabbit IgG 형식이며, 고순도 Protein A/G 정제 및 안정적 PBS 버퍼 기반 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
| Functional Assay (Functional) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BSG/6468R |
| Immunogen | Recombinant full-length human BSG protein (CD147, UniProt ID: P35613-1, antigen range 1–385) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein important in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 belongs to the immunoglobulin superfamily and shows high expression in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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