Thermo Fisher Scientific PRPF18 Polyclonal Antibody
Rabbit polyclonal antibody against human PRPF18 protein. Validated for Western blot at 1:500–1:1,000 dilution. Supplied as a liquid, 1 mg/mL concentration. Suitable for research use only, not for diagnostic or resale purposes.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human PRPF18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555947 |
Target Information
PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10-associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency, and trisomy 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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