Thermo Fisher Scientific Cathelicidin Polyclonal Antibody
Cathelicidin 단백질을 검출하는 토끼 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합. 인간, 마우스, 랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAMP (Accession P49913), corresponding to amino acid residues I43–S93 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852279 |
Product Specific Information
Antibody detects endogenous levels of total Cathelicidin.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin and have roles in mediating innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment.
Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate immune response.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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