Thermo Fisher Scientific NFATc3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NFATc3 protein. Validated for Western blot and immunoprecipitation. Supplied as a liquid, unconjugated form at 1 mg/mL. Recommended storage at 4°C. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 700 and 750 of human Nuclear Factor of Activated T-cells, Cytoplasmic, Calcineurin-dependent 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.
mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).
When translation ends upstream from the last exon-exon junction, NMD is triggered to degrade mRNAs containing premature stop codons.
This protein is located only in the cytoplasm and interacts with a protein homologous to yeast Upf2p to trigger mRNA decapping.
Use of multiple polyadenylation sites has been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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