Thermo Fisher Scientific OTX2 Polyclonal Antibody
OTX2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western Blot에 최적화되어 있습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific OTX2 Polyclonal Antibody
Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (27 PSVGYPATPRKQRRERT 43) of OTX2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2540928 |
Product Specific Information
PA5-23406 is predicted to react with mouse due to 100% homology.
Target Information
OTX2 is a 289-amino-acid protein belonging to the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms, though other isoforms cannot be excluded. OTX2 serves as an early marker of endodermal differentiation in embryonic stem cells and may play a role in brain and sensory organ development.
The protein binds to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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