Thermo Fisher Scientific WIPI1 Monoclonal Antibody (2D1)
WIPI1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 자가포식 관련 연구에 유용하며, 인간 WIPI1 단백질에 반응합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | WIPI1 (NP_060453.2, 348–445 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GGECVLIKTH SLLGSGTTEE NKENDLRPSL PQSYAATVAR PSASSASTVP GYSEDGGALR GEVIPEHEFA TGPVCLDDEN EFPPIILCRG NQKGKTKQ
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins.
WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas, and skeletal muscle. WIPI1 is upregulated in various tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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