Thermo Fisher Scientific HES5 Monoclonal Antibody (OTI6F7), TrueMAB
HES5 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 정제된 항체로 재조합 HES5 단백질을 면역원으로 사용했습니다. PBS 완충액에 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F7 |
| Immunogen | Full length human recombinant protein of human HES5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HES5 acts as a downstream effector of the Notch signaling pathway and is expressed in advanced ovarian serous adenocarcinomas and cervical squamous carcinoma.
It is also reported to be abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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