Thermo Fisher Scientific TRAPPC10 Polyclonal Antibody

Applications

• Western Blot (WB): Tested at 1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence: IVDKIRNDFC NKQSDRCVVL SDPLKDSSRT QESWNAFLTK LRTLLLMSFT
• Sequence homology:
  • Cow: 100%
  • Dog: 100%
  • Guinea Pig: 100%
  • Horse: 100%
  • Human: 100%
  • Mouse: 100%
  • Rat: 100%
  • Zebrafish: 79%

Target Information

TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein), or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein, with conserved structure and function. Localized to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi as part of the multisubunit transport protein particle (TRAPP) complex. Mutations in the TRAPPC10 gene may be associated with autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive progressive myoclonic epilepsy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.