Thermo Fisher Scientific HMBS Monoclonal Antibody (OTI1F1)
HMBS 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. 인간 유래 단백질에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA526541
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F1 |
| Immunogen | Full length human recombinant protein of HMBS produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724459 |
Target Information
PBGD (porphobilinogen deaminase), also known as hydroxymethylbilane synthase (HMBS), is a cytoplasmic enzyme involved in the heme biosynthesis pathway. Deficiency of PBGD results in impaired pyrrole metabolism, leading to the inherited autosomal disorder acute intermittent porphyria (AIP).
AIP is characterized by acute neurological dysfunctions such as hypertension, tachycardia, peripheral neuropathy, abdominal pain, and elevated urinary levels of aminolevulinic acid and porphobilinogen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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