Thermo Fisher Scientific RAB9 Polyclonal Antibody
RAB9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성 보유. 고순도 친화 크로마토그래피 정제, PBS/glycerol 버퍼에 보존. 연구용으로만 사용.
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Thermo Fisher Scientific RAB9 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB9A (Accession P51151), corresponding to amino acid residues L72–L122 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850496 |
Product Specific Information
Antibody detects endogenous levels of total Rab9.
Target Information
Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell.
Rab9 is required for trafficking mannose 6-phosphate receptor between the late endosome and trans-Golgi network (TGN). By facilitating receptor transport, Rab9 enables cells to efficiently recycle important cellular trafficking components.
Rab9, like other Rab family members, must be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated Rab9 is membrane-bound; however, 10–20% of the cellular pool of Rab9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP-bound Rab9 from their fusion targets back to their membranes of origin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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