Thermo Fisher Scientific PREX2 Polyclonal Antibody
PREX2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 인간 유래 N-말단 합성 펩타이드로부터 제작되었으며, 다양한 종에서 높은 상동성을 보입니다. 액상 형태로 제공되며, -20°C에서 보관 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human PREX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689543 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 86%
Target Information
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner and may act as an important mediator of Rac signaling downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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