Thermo Fisher Scientific Beta crystallin S Polyclonal Antibody, Biotin
Beta crystallin S 단백질을 인식하는 Biotin 결합 폴리클로날 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity chromatography 정제. 안정적 보관(-20°C) 가능.
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Thermo Fisher Scientific Beta crystallin S Polyclonal Antibody, Biotin
Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH and covalently modified, corresponding to N-terminal amino acids 19–37 of mouse Beta crystallin S protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8), with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme type) and ubiquitous. The ubiquitous class constitutes the major proteins of vertebrate eye lens, maintaining transparency and refractive index. Lens fiber cells lose their nuclei during development, so crystallins remain throughout life, making them extremely stable. Mammalian crystallins are divided into alpha, beta, and gamma families. Beta and gamma crystallins form a superfamily, with alpha and beta further subdivided into acidic and basic groups. Crystallins contain seven regions: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are monomeric, highly symmetrical proteins lacking connecting peptides and terminal extensions, and are differentially regulated after early development. The encoded protein was initially considered a beta-crystallin but shows greater similarity to gamma-crystallins, being the most significant gamma-crystallin in adult lens tissue. Aging or mutations in these genes are associated with cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: BXTL200-BIOTIN_CRYGS_O35486-1_Rabbit.svg, BXTL200-BIOTIN_CRYGS_O35486-1_Rabbit_PDP.jpeg)
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